Ghigo et al (& Sala, Hirsch), Science Translational Medicine
“A non-catalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage”
Lupieri et al (& Ghigo, Hirsch), Journal of Cell Science.
“Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis”
Campa et al (& Sala, Hirsch), Nature Communications.
“Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs”.
Pirali et al (& Hirsch), ChemMedChem.
“Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases”
Ghigo et al (& Hirsch), Circulation.
“Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase {gamma} Activity in Pressure Overload-Induced Cardiac Failure”
Damilano et al (& Ghigo, Hirsch), Circulation.
“Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma”
Vecchione et al (& Hirsch), Journal of Experimental Medicine.
“PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects”
Patrucco et al (& Hirsch), Cell.
“Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation”
Hirsch et al, Science.